Skrine suffered a concussion last week at Miami and has been in the league’s protocol for head injuries. He sat out practice all week, and coach Todd Bowles ruled him out Friday.
Bowles declined to reveal who would replace Skrine, although Juston Burris and Darryl Roberts are listed as backups. Skrine also plays in the slot when the Jets shift to a nickel package and contributes on special teams.
Defensive end Muhammad Wilkerson is questionable with shoulder and foot ailments, but has played through them this season.
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